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A Comparison of MRI Criteria for Diagnosing Pediatric ADEM and MS Neurol 74:1412-1415, 1404, Ketelslegers,I.A., et al, 2010 See this aricle in Pubmed Article Abstract The results in our cohort demonstrate that the new Callen criteria for multiple sclerosis-acute disseminated encephalomyelitis (MS-ADEM) are the most useful for differentiating a first attack of MS from monophasic ADEM. Although the Callen diagnostic MS criteria are more sensitive, they lack the specificity necessary to differentiate MS from ADEM.

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